Conrad Fischer, Ph.D.

- Cardiovascular active peptides and GPCR receptor signaling - Viral protease inhibitors - Nature-inspired supramolecular inclusion hosts

JOINED BARRY: JANUARY 2021. COURSES CHE 343, CHE 343L Organic Chemistry with Lab, I CHE 344, CHE 344L Organic Chemistry with Lab, II CHE 352, CHE 352L Biochemistry I with Lab CHE 395, CHE 495 Research SELECTED PUBLICATIONS Fischer, C.; Lamer, T.; Fernandez, K.; Gheblawi, M.; Wang, W.; Pascoe, C.; Lambkin, G.; Iturrioz, X.; Llorens-Cortes, C.; Oudit, G.Y.; Vederas, J.C. Optimizing PEG-extended apelin analogues as cardioprotective drug leads. Importance of the KFRR motif and aromatic head group for improved physiological activity. J. Med. Chem., 63, 12073-12082, 2020 Vuong, W.; Khan, M.B.; Fischer, C.; Arutyunova, E.; Lamer, T.; Shields, J.; Bandi, H.; McKay, R.T.; van Belkum, M.J.; Joyce, M.; Young, H.S.; Tyrrell, L.; Vederas, J.C.; Lemieux, M. J. Feline coronavirus drug inhibits the main protease of SARS-CoV-2 and blocks virus replication, Nature Commun., 11, 4282, 2020 Fischer, C. A patent review of apelin receptor modulators (2014-2019), Expert Opin. Ther. Pat., 30, 251-261, 2020 Masoud, A.G.T.; Lin, J.X.; Farhan, M.A.; Fischer, C.; Zhu, L. F.; Anderson, C. C.; Sis, B.; Kassiri, Z.; Moore, R. B.; Kim, D.; Vederas, J. C.; Adam, B. A.; Oudit, G. Y.; Murray, A. G. Apelin directs endothelial cell differentiation and vascular repair following immune-mediated injury, J. Clin. Invest., 130, 94-107, 2020 SELECTED CONFERENCE PRESENTATIONS Apelin analogues as novel cardioprotective drugs, 102nd Canadian Chemistry Conference and Exhibition, June 2019, Quebéc, Canada PEGylated apelin analogues as cardiovascular active drugs, 101st Canadian Chemistry Conference and Exhibition, May 2018, Edmonton, Canada Apelin as key peptide for heart disease treatment, 1st RSC Anglo-Nordic Medical Chemistry Symposium, June 2017, Snekkersten Conference Center, Helsingør, Denmark Engineered apelin and natriuretic peptides as potent therapeutics for the treatment of cardiovascular diseases. Invited talk, June 2017, University of Lincoln, Lincoln, UK Apelin as key peptide for heart disease treatment. 34th European Peptide Symposium, September 2016, University of Leipzig, Leipzig, Germany Laterally modified calix[4]arenes as potential sensor materials. 20th Junior Research-Symposium in Bioorganic chemistry, September 2011, KIT Karlsruhe, Karlsruhe, Germany HONORS / AWARDS 2016-2018 Postdoctoral Fellowship, Alberta Innovates Health Solutions 2014-2015 Postdoctoral Fellowship, Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) 2008 M.Sc. thesis award, Agricola Medal and Price for best MSc thesis in 2008, University Freiberg, Germany PROFESSIONAL MEMBERSHIPS ACS – American Chemical Society, 2021-present CSC – Canadian Society of Chemistry, 2018-present GDCh – German Chemical Society, 2008-present CONTACT INFORMATION Office: Wiegand 128A Telephone: 305-899-3430 Fax: 305-899-3479 E-mail: cfischer@barry.edu QUICKLINKS Engaged STEM scholars STEM Learning Community Browse & Apply for Scholarships APPLY NOW REQUEST INFORMATION ASK US A QUESTION SCHEDULE A VISIT